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glossary:vegf-c [2007/09/07 17:26]
Pat O'Connor
glossary:vegf-c [2012/10/16 14:40] (current)
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 +Abbreviation for Vascular Endothelial Growth Factor C.  An under expression of this gene has been found and/or is believed to be responsible for Milroy'​s Disease (Milroy'​s Syndrome), [[glossary:​hereditary lymphedema 1|Hereditary Lymphedema I]].
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 +An over expression of VEGF-C is indicative of [[lymphatic]] ([[cancer]]) metastasis.
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 +The protein encoded by this gene is a member of the platelet-derived growth factor/​vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of [[blood vessels]]. This secreted [[protein]] undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D. 
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 +* [[:​Lymphedema]]
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 +* [[:​Pathophysiology of Lymphedema]]
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 +* [[:milroys syndrome|Milroy'​s Syndrome]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​lymphedema_genetics.htm| Lymphedema Genetics]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=16|Genetics,​ Research, Lymphangiogenesis,​ Angiogenesis]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=1025|VEGF and its relationship to inflammatory mediators.]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=963|A novel VEGFR3 mutation causes Milroy disease.]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=847|Roles of VEGFR-2 and VEGFR-3 signaling in adult lymphangiogenesis]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=613|VEGF and PlGF promote adult vasculogenesis]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=612|PIGF antagonizes VEGF induced angiogenesis - tumor growth]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=610|Interaction of VEGF-C and VEGF-D with neuropilin receptors]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=585|Lymphatic hyperplasia,​ VEGF-C upregulation,​ MMP-9.]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=581|Milroy'​s Disease (lymphedema) and the VEGFR3 (FLT3)]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​lymphangiogenesis_formation_of_lymphatic_vessels_and_malignancy.htm|The Formation of Lymphatic Vessels and Its Importance in the Setting of Malignancy]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​lymphangiogenesis_breast_cancer_vegfc.htm|Lymphangiogenesis Breast Cancer the VEGF-C]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​lymphangiogenesis_and_gastric_cancer.htm|Lymphangiogenesis and Gastric Cancer]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​lymphangiogenesis_in_head_and_neck_cancer|Lymphangiogenesis in Head and Neck Cancer]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​lymphangiogenesis_and_kaposis_sarcoma_vegfc.htm| Lymphangiogenesis and Kaposi'​s Sarcoma VEGF-C]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​lymphangiogenesis_and_melanoma|Lymphangiogenesis and Melanoma]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​Lymphangiogenesis_in_Wound_Healing| Lymphangiogenesis in Wound Healing]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​a_model_for_gene_therapy_of_human_lymphedema.htm|A model for gene therapy of human hereditary lymphedema]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​vegfr3_ligands_lymphangiogenesis_1.htm|VEGFR-3 Ligands and Lymphangiogenesis (1)]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​vegfr3_ligands_lymphangiogenesis_2.htm|VEGFR-3 Ligands and Lymphangiogenesis (2)]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​vegfr3_ligands_lymphangiogenesis_3.htm|VEGFR-3 Ligands and Lymphangiogenesis (3)]] 
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 +[[http://​www.lymphedemapeople.com/​thesite/​Vascular_Endothelial_Growth_Factor_VEGF|Vascular Endothelial Growth Factor; VEGF]] ​
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 +[[http://​www.lymphedemapeople.com/​thesite/​VEGFD_Angiogenic_Lymphangiogenic_Effector.htm|VEGF-D is the strongest angiogenic and lymphangiogenic effector]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​Inhibition_of_Lymphatic_Regeneration_by_VEGFR3|Inhibition of Lymphatic Regeneration by VEGFR3]]
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 +[[http://​www.lymphedemapeople.com/​thesite/​VEGFR3_and_Metastasis_in_Prostate_Cancer|VEGFR3 and Metastasis in Prostate Cancer]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=1115|Radiogeneic Lymphangiogenesis in the Skin]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=720|Dose-dependent response of FGF-2 for lymphangiogenesis]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=630|Lymphangiogenesis Signalling Pathways in Human Disease]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=616|Lymphangiogenesis,​ inflammation and metastasis]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=611|Lymphatic endothelial cells, lymphangiogenesis,​ cell matrix]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=583|Influence of IFN- alpha and IFN- gamma on Lymphangiogenesis.]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=582|Expression of VEGF-C angiogenesis,​ lymphangiogenesis Cancer]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=579|VEGF-C gene therapy, Lymphangiogensis and Lymphedema]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=144|Molecular lymphangiogenesis:​ new players.]]
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 +[[http://​www.lymphedemapeople.com/​phpBB2/​viewtopic.php?​t=1084|Genetics Glossary]]
  
glossary/vegf-c.txt ยท Last modified: 2012/10/16 14:40 (external edit)