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glossary:blood-brain_barrier [2012/10/16 14:40] (current)
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|+||Unlike other tissues in the body, the brain tissue is provided with a tight endothelial layer on vessels that acts as a filter for substances that reach the brain through the [[blood]] stream. This filter is called the bloodbrain barrier. The bloodbrain barrier is responsible for the absence of contrast enhancement in normal brain tissue after administration of the iodinated or gadopentate contrast media used in CT and MR diagnostic imaging. The absence of contrast uptake in normal [[tissue]] provides the basis for differentiation from pathological brain tissue which is conversely characterized by a disruption of the bloodbrain barrier.|